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Hantavirus (Andes) vs Marburg

How does Andes hantavirus actually compare to the other emerging viruses people most often ask about? All figures sourced directly from WHO and CDC fact sheets.

Last reviewed: 2026-05-09

Hantavirus (Andes) vs Marburg

Comparison of seven viral diseases by case fatality rate, R0, incubation, transmission, treatment and reservoir host.
MetricANDVMVD
Case fatality rate30–40%~50% (range 24–88%)
R0 (basic reproduction number)<1 (rare P2P clusters)1–2
Incubation period2–4 weeks (up to 6)2–21 days
Transmission modeInhaled rodent excreta; rare person-to-person (ANDV only)Direct contact with body fluids; bat exposure (caves)
Person-to-person spreadLimitedYes
Treatment availableSupportive care, oxygen, ECMO; ribavirin investigationalSupportive care; investigational antibodies and antivirals
Vaccine availableNone licensedNone licensed (Sabin/cAd3-Marburg in trials)
Geographic distributionArgentina, Chile, with imported clusters worldwide (2026)Sub-Saharan Africa; rare exports
First identified19951967
Virus familyHantaviridae (Bunyavirales)Filoviridae
Reservoir hostLong-tailed pygmy rice rat (Oligoryzomys longicaudatus)Egyptian rousette fruit bat (Rousettus aegyptiacus)

Hantavirus (Andes virus, ANDV)

ANDV

Andes virus is the only hantavirus with documented person-to-person transmission. The 2026 MV Hondius cluster is being closely watched because its cruise-ship setting matches the close-contact conditions where ANDV chains have appeared historically.

First identified
1995
Virus family
Hantaviridae (Bunyavirales)
Reservoir host
Long-tailed pygmy rice rat (Oligoryzomys longicaudatus)

Marburg virus disease

MVD

Marburg shares transmission and clinical features with Ebola but no licensed vaccine yet exists. Outbreaks have been small and contained through case isolation and safe burial practices.

First identified
1967
Virus family
Filoviridae
Reservoir host
Egyptian rousette fruit bat (Rousettus aegyptiacus)

Sources: WHO and US CDC topic pages.

Disease comparison