Changelog

Post-quarantine wrap-up: DON-604 (missed from June 10 update) integrated; ECDC reclassification; quarantine end June 18; Saint Helena closed June 8; NAVIS initiative; MV Hondius Arctic return. Headline unchanged: 18 cases, 15 countries, 3 deaths.

• •WHO DON-604 (28 May 2026) integrated — missed in previous update: 13 cases (11 confirmed + 2 probable), 3 deaths, CFR 23%. Three new cases since DON-601: Canada (16 May), Netherlands crew member (22 May), Spain Case 3 (25–26 May). 600+ contacts across 32 countries. Rt=0.7 as of 22 May (declining). DON title change: 'Multi-country' → 'Multi-locations'. lastDon updated to DON-604, lastDonDate 2026-05-28.
• •ECDC 17 June 2026 update: reclassification from 11 confirmed + 2 probable → 12 confirmed + 1 probable = 13 total cases, 3 deaths, CFR 23%. One previous probable reclassified to confirmed. lastEcdcUpdate updated to 2026-06-17.
• •Saint Helena government (8 June): declared hantavirus incident concluded — no active, suspected, or confirmed cases. South Atlantic component fully resolved. SH country note updated.
• •NAVIS launched (12 June): 21-country coordinated Andes virus natural history study (WHO + Hospital Germans Trias i Pujol + ANRS-MIE + CORC, ISARIC framework). Timeline and news entries added.
• •MV Hondius (13 June): departed Longyearbyen for first post-outbreak Arctic expedition (North Spitsbergen, 13–20 June). Timeline entry added.
• •Quarantine ends (18 June): RIVM confirms almost all passengers/crew completed 42-day quarantine; all retests negative. One Dutch national (late-May positive) remains hospitalised; one weak-positive subsequently cleared. Timeline and news entries added.
• •WHO quarantine confirmation (19 June): quarantine lifting confirmed for last remaining monitored contacts.
• •HantaCount headline unchanged: 18 cases, 15 countries, 3 deaths, CFR 17%.
• •methodology.lockedAt updated to 2026-06-21

US 42-day monitoring period ended (6 June) with no new cases. MV Hondius decontamination completed (29–30 May); ship departed Rotterdam 6 June for Longyearbyen. No new cases since May 25–26 (Spain Case 3). Headline unchanged: 18 cases, 15 countries, 3 deaths.

• •US country note updated: 42-day monitoring period for all 18 American passengers ended 6 June 2026 with no hantavirus cases detected. No further public-health follow-up required.
• •Timeline entry added (2026-05-30): MV Hondius decontamination completed in Rotterdam by EWS Group (13 biosecurity experts, all 8 decks, rodent-free certified). Ship cleared by Dutch authorities; departed Rotterdam 6 June for Longyearbyen.
• •Timeline entry added (2026-06-06): US 42-day monitoring period ends, zero cases detected, all passengers released.
• •HantaCount headline unchanged: 18 cases, 15 countries, 3 deaths, CFR 17%.
• •WHO official count unchanged: 13 cases, 3 deaths, CFR 23%.
• •No new WHO DON since DON-601 (13 May). No new ECDC update beyond 26 May (13 cases).
• •methodology.lockedAt updated to 2026-06-10

Spain 3rd case confirmed (25–26 May); WHO total 12 → 13; ECDC 26 May update (11 confirmed + 2 probable = 13). Tristan da Cunha patient recuperating at home. Headline: 17 → 18 cases.

• •Spain: 3rd case confirmed — a second Spanish national quarantined at Gómez Ulla Hospital (Madrid) tested PCR-positive during routine periodic diagnostic screening (25–26 May). Cases 2 → 3. lastEvent: 2026-05-12 → 2026-05-26.
• •HantaCount headline: 17 → 18 cases (+1 Spain). CFR: 18% → 17% (3/18 = 16.7%). Deaths unchanged at 3. Countries unchanged at 15.
• •WHO official count: 12 → 13. labConfirmed: 10 → 11. CFR: 25% → 23% (3/13 = 23%). WHO DG Tedros: 'Spain reported a new case among the passengers who are in quarantine, which brings the total number of cases to 13. The situation remains stable.'
• •ECDC 26 May 2026 update: 11 confirmed + 2 probable = 13 total cases, 3 deaths, CFR 23%. 1 new case since 24 May. Case definition revised to align with WHO: confirmed now includes PCR and/or serology. lastEcdcUpdate: 2026-05-24 → 2026-05-26.
• •Tristan da Cunha (23 May gov update): suspected case now well enough to recuperate at home; still classified as probable pending final laboratory confirmation. SH lastEvent updated to 2026-05-23.
• •Nebraska quarantine: 18 US passengers remain at facility, requested through 31 May (21-day mark). No new US cases.
• •France ECMO patient: stable but critical; no further deterioration reported through late May.
• •MV Hondius: decontamination at Rotterdam ongoing; return to service 13 June from Longyearbyen confirmed.
• •methodology.lockedAt updated to 2026-05-29

12th WHO case confirmed: Dutch crew member tested positive in NL surveillance (22 May). ECDC 24 May update incorporated. Headline: 16 → 17 cases.

• •Netherlands: 3rd case confirmed — Dutch crew member repatriated from Tenerife tested positive during weekly RIVM + Erasmus MC surveillance in NL quarantine (22 May 2026). Precautionary hospitalisation, stable.
• •HantaCount headline: 16 → 17 cases (+1 Netherlands crew). CFR: 19% → 18% (deaths unchanged at 3)
• •Countries unchanged at 15 (Netherlands already counted)
• •WHO official count: 11 → 12 (Tedros press statement 22 May, designating Dutch crew member as 12th case). labConfirmed: 9 → 10. CFR (official): 27% → 25%
• •ECDC 24 May 2026 update: 10 confirmed + 2 probable = 12 total cases, 3 deaths, CFR 25%. 1 new case, 0 new deaths since 21 May.
• •ECDC lastEcdcUpdate: 2026-05-21 → 2026-05-24
• •Spain Madrid patient (Gómez Ulla): progressing well, symptom-free as of 19 May (no change)
• •France ECMO patient: stable but critical, no further deterioration reported through 24 May
• •Nebraska CDC quarantine: 18 US passengers continue under quarantine through 31 May; legal challenges expected per Healthbeat (22 May)
• •MV Hondius: disinfection at Rotterdam continues; return to service 13 June from Longyearbyen
• •Tristan da Cunha: GeneXpert community screening results still pending; case remains classified as probable
• •methodology.lockedAt updated to 2026-05-25

No new cases. Rotterdam arrival details corrected (18 May); CDC quarantine orders; Spain patient progress; ECDC 21 May update; WHO official count fixed.

• •No new cases or deaths since 16 May (Canada). HantaCount headline: 16 cases, 15 countries, 3 deaths, CFR 19%
• •MV Hondius arrival date corrected: 17 May → 18 May (Oceanwide press release 18 May 19:30 CET)
• •Rotterdam details updated: 20 non-Dutch crew (17 Filipino, 3 Ukrainian) in 6-week shipping-container quarantine at port; body removed for cremation; EWS Group decontamination; return to service 13 June from Longyearbyen
• •CDC quarantine orders (18 May): formal orders issued for 2 US passengers under Public Health Service Act; all 18 requested to remain at Nebraska through 31 May; legal challenges reported as of 22 May
• •Spain: Madrid patient (Gómez Ulla) 'progressing well' (19–21 May); 13 ward contacts allowed visitors with PPE after testing negative
• •ECDC 21 May update: no new cases; 9 confirmed + 2 probable = 11 total; CFR 27%; risk very low
• •WHO official count corrected: 12 → 11 (US inconclusive case cleared 13 May was not removed from total in previous update; Canada adds back as 9th confirmed); inconclusive field: 1 → 0; CFR: 25% → 27%
• •ECDC lastEcdcUpdate: 2026-05-16 → 2026-05-21
• •NEJM correspondence published: NEJMc2606496 — first peer-reviewed clinical description of MV Hondius cluster
• •methodology.lockedAt updated to 2026-05-22

Canada confirmed case; MV Hondius arrives Rotterdam. Headline: 15 → 16, countries: 14 → 15.

• •Canada: new confirmed case — returned BC passenger tests presumptively positive (ECDC 16 May); mild symptoms, home quarantine. Canada cases: 0 → 1
• •HantaCount headline total: 15 → 16 cases
• •Countries: 14 → 15 (Canada now confirmed)
• •CFR: 20% → 19% (deaths unchanged at 3)
• •WHO official labConfirmed: 8 → 9; WHO total: 11 → 12
• •ECDC lastEcdcUpdate: 2026-05-14 → 2026-05-16
• •MV Hondius arrives Rotterdam (17 May); 23 temporary quarantine cabins installed at port for crew
• •Oceanwide Expeditions to announce ship's return-to-service timeline by end of week
• •methodology.lockedAt updated to 2026-05-17

US case cleared (NEGATIVE); Italy 4 contacts negative; France 26 contacts negative; WHO MCM consultation. Headline: 16 → 15.

• •US case reclassified non-case: Dr. Stephen Kornfeld retested NEGATIVE at UNMC (13 May) — released from biocontainment; US cases 1 → 0
• •HantaCount headline total: 16 → 15 cases; CFR: 19% → 20%
• •Italy: all 4 quarantined KLM flight contacts tested negative at Spallanzani (Rome) + Milan lab; Italy NOT added to country list
• •France: Health Minister confirms all 26 close contacts PCR-negative; Case 1 (ECMO) stable, no further deterioration
• •Spain Case 2 (Madrid, Gómez Ulla): mild fever + respiratory symptoms, stable, no critical progression as of 15 May
• •WHO + UKHSA: Emergency Scientific Consultation on Andes Virus MCM R&D (vaccines/antivirals) — 15 May, Geneva
• •ECDC 14 May update: no new cases or deaths; risk remains very low
• •MV Hondius: at sea en route Rotterdam, expected arrival 17–18 May
• •Tristan da Cunha GeneXpert community screening results: still pending as of 15 May
• •whoOfficial.lastEcdcUpdate updated to 2026-05-14
• •methodology.lockedAt updated to 2026-05-15

France ECMO; Italy KLM flight contact; Spain symptom onset; Radboud cleared; flights #2-3 negative; ECDC lab guidance.

• •France Case 1: critically ill on ECMO (extracorporeal membrane oxygenation) — first Hondius patient requiring artificial-lung support
• •Italy: 25yo Italian man on KLM Johannesburg-Amsterdam (25 April) developed compatible symptoms; 4 Italians under precautionary quarantine — first off-ship flight-contact exposure
• •Spain Case 2 (Madrid): developed low-grade fever + mild respiratory symptoms — previously asymptomatic
• •Radboud UMC: all 12 quarantined Nijmegen staff blood-tested negative; staff stay in 6-week observation
• •Repatriation flights #2 + #3 — all passengers tested negative for hantavirus
• •ECDC: new 'Advice on laboratory testing of ANDV for high-risk contacts' guidance — handles discordant-result cases
• •ECDC quarantine call: LIFT St. Helena-Johannesburg (24 Apr) + KLM Johannesburg-Amsterdam (25 Apr) high-risk passengers
• •Italy not added to country totals pending Italian health authority case classification
• •HantaCount headline total unchanged: 16 cases, 3 deaths, 14 countries

WHO DON-601 integrated: US case reclassified as inconclusive (discordant labs); sequencing confirms single spillover.

• •WHO reference: DON-600 → DON-601 (published 13 May 2026)
• •lastDonDate: 2026-05-08 → 2026-05-13
• •deathsConfirmed/deathsProbable fields added (2 confirmed + 1 probable per DON-601)
• •WHO global risk assessment: very low → low (moderate for those on board)
• •US case (Nebraska biocontainment): WHO DON-601 reclassifies as inconclusive — discordant PCR results between two labs, retesting under way
• •Preliminary sequencing: cases differ by ≤1 SNP → single zoonotic spillover event (likely pre-boarding land exposure in Argentina/Chile, bird-watching hypothesis)
• •Working hypothesis: index case acquired infection on land before boarding; subsequent human-to-human transmission onboard
• •MV Hondius: sailing to Netherlands with 25 crew + 2 Dutch health workers
• •ECDC reclassification harmonised with WHO DON-601
• •Atlanta symptomatic case: PCR negative — hantavirus ruled out
• •Illinois Winnebago County SNV case added as news item (separate strain, not cruise ship)
• •HantaCount headline total unchanged: 16 cases, 3 deaths, 14 countries

Cases rise to 14; contacts traced jump to 144 across 13 countries; France and Singapore added.

• •Cases 13 → 14 (+1)
• •Deaths unchanged at 3
• •Countries 11 → 13 (added France, Singapore)
• •Contacts traced 58 → 144 (+86)
• •CFR field added: 21.4%
• •WHO Director-General travels to Tenerife to coordinate MV Hondius disembarkation

No data change. Methodology, sources and changelog pages added.

• •Published /methodology — full inclusion criteria, source hierarchy and de-duplication rules.
• •Published /sources — primary-source register (18 entries).
• •Published /changelog — public audit trail of dataset edits.

Cluster expands to 11 countries; contacts traced more than double.

• •Cases 10 → 13 (+3)
• •Deaths unchanged at 3
• •Countries 7 → 11 (added Spain, United States, South Africa, Saint Helena)
• •Contacts traced 30 → 58 (+28)
• •Critical unchanged at 1

First European case outside the Netherlands; tracing scales out.

• •Switzerland first confirmed European case outside NL.
• •Reuters confirms tracing across 12+ countries.
• •ECDC RRA reaffirmed: risk for Europe assessed as very low.

ECDC publishes Rapid Risk Assessment.

• •Risk for general European population assessed as very low.
• •Recommendation: trace disembarked passengers.

WHO Disease Outbreak News (DON-599) issued.

• •Initial public dataset (10 cases, 7 countries, 30 contacts).
• •Andes virus (ANDV) confirmed by PCR.